Valorisation of Three Underutilised Native Australian Plants: Phenolic and Organic Acid Profiles and In Vitro Antimicrobial Activity

Tasmannia lanceolata, Diploglottis bracteata and Syzygium aqueum are understudied native Australian plants.This study aimed to characterise the non-anthocyanin phenolic and organic acid profiles of the aqueous extracts obtained from the leaves of T.lanceolata and fruits of D.bracteata and S.aqueum by UHPLC-Q-Orbitrap-MS/MS and UHPLC-TQ-MS/MS.A tota

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Identification of Ftr1 and Zrt1 as iron and zinc micronutrient transceptors for activation of the PKA pathway in Saccharomyces cerevisiae

Multiple types of nutrient transceptors, membrane proteins that combine a transporter and receptor function, have now been established in a variety of organisms.However, so far all established transceptors utilize one of the macronutrients, glucose, amino acids, ammonium, nitrate, phosphate or sulfate, as substrate.This is also true for the Sacchar

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Development, clinical utility, and place in therapy of posaconazole for prevention and treatment of invasive fungal infections

Emily Zoller, Connie Valente, Kyle Baker, Michael E KlepserFerris State University College of Pharmacy, Kalamazoo, Michigan, USAAbstract: Posaconazole is an extended-spectrum azole antifungal that exhibits activity against a broad range of fungal pathogens, including yeasts and moulds.Clinical data have demonstrated the clinical utility of posacona

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